To date, greenhouse gas (GHG) emissions, mitigation strategies and the accompanying health co-benefits in different economic sectors have not been fully investigated. The purpose of this paper is to review comprehensively the evidence on GHG mitigation measures and the related health co-benefits, identify knowledge gaps, and provide recommendations to promote further development and implementation of climate change response policies.

Many recent major studies, including the IPCC’s Fourth Assessment Report, have attested that energy efficiency is humanity’s prime option to combat climate change in the short- to mid-term. The potential to avoid CO2 emissions cost-effectively has been reported to be significant through efficiency policies. However, the review of global research findings on the quantification of cost-effectiveness of opportunities through improved efficiency has highlighted that there is a major shortcoming in the vast majority of such calculations.

An overview of climate change mitigation opportunities in the world's buildings is presented, based on the key building-specific findings of the Fourth Assessment Report from the Intergovernmental Panel of Climate Change. Buildings and the building stock can play a major role in mitigating climate change in the short- to medium-term, since substantial reductions in CO2 emissions from their energy use can be achieved over the coming years.