Energy efficiency (i.e., the ratio of output of performance to input of energy) in office buildings can reduce energy costs and CO2 emissions, but there are barriers to widespread adoption of energy efficient solutions in offices because they are often perceived as a potential threat to perceived comfort, well-being, and performance of office users. However, the links between offices' energy efficiency and users' performance and well-being through their moderators are neither necessary nor empirically confirmed.

There are indications that energy-retrofitted buildings can create risks for indoor environmental quality (IEQ) and therefore for health and comfort of occupants. A review was conducted to identify and verify those risks, within three themes: building envelope, heating, ventilating and air conditioning (HVAC)-systems, and occupants. Publications from the last five years in major peer-reviewed journals from different fields (energy, buildings, indoor air, social sciences) were found by using a variety of keywords (health effects, occupant behaviours, energy-efficient retrofitting, etc.).